RADIOBIOLOGICAL STUDIES ON PHAGE INDUCTION IN LYSOGENIC STRAINS (I)
نویسندگان
چکیده
منابع مشابه
Observations on phage output and on anaerobic lysis of lysogenic strains of Bacillus megatherium.
The phenomenon of lysogenicity is an interesting aspect of the bacteriumbacteriophage relationship, for this is an instance of host cells capable of carrying virus through an infinite succession of subcultures, even through cycles of sporulation (den Dooren de Jong, 1930, 1932). Unlike other bacterium-bacteriophage systems, infection of the host does not inevitably terminate in its destruction;...
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In toxigenic Vibrio cholerae, the CTX genetic element which carries the genes for cholera toxin (CT) is the genome of a lysogenic bacteriophage (CTXPhi). Clinical and environmental strains of V. cholerae O1 or O139 and stools that were culture positive for cholera were analyzed to study the induction and transmission of CTXPhi. To our knowledge, this is the first report of the examination of CT...
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1. Lysogenic B. megatherium 899a was adapted to growth in a minimal ammonium sulfate medium (ASCM). 2. Adaptation took place slowly and the following changes in the culture occurred: (a) The growth rate increased from 0.5 to 1.5-2.0/hr. (b) The culture changed from diffuse to mucoid. (c) The total phage titer, and the gelatinase concentration decreased to 1/100 or less. (d) The types of phage p...
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Temperate bacteriophage can transfer toxin-encoding genes between bacteria, often resulting in acquired pathogenicity. However, little is known regarding the effects of the eukaryotic host on the phage-pathogen interaction. Using Streptococcus pyogenes as a model, we demonstrate, both in vitro and in vivo, that the eukaryote mediates the efficient induction of toxin-encoding temperate phage and...
متن کاملThe Action of Streptonigrin on Bacterial Dna Metabolism and on Induction of Phage Production in Lysogenic Bacteria.
Net DNA synthesis is preferentially inhibited in Salmonella typhimurium by treatment with the antibiotic streptonigrin. As with other agents that affect DNA synthesis, short exposures to streptonigrin result in excellent induction of phage production in inducible lysogenic bacteria. Moreover, these cells produce good yields of active phage when maintained in the presence of the inhibitor until ...
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ژورنال
عنوان ژورنال: Uirusu
سال: 1959
ISSN: 0042-6857,1884-3433
DOI: 10.2222/jsv.9.16